By: Savanna Perry, PA-C
Most PA programs require a similar set of prerequisite classes: two semesters each of biology, general chemistry, and anatomy and physiology (all with labs), plus statistics or biostatistics. Recommended additions include psychology, microbiology, and sometimes organic chemistry or biochemistry. Your major matters less than the specific classes you take, so always check each program's exact list.
When it comes to the classes required to get into PA school, most programs are pretty similar across the board. Occasionally one program will be pickier than another or require a few more courses, but the basics tend to be the same.
If you already have a bachelor's degree and you are going back to take classes, it is easier to pick and choose exactly what you need. Some schools require that courses be completed within a certain window, like the last 5 or 10 years, while others accept coursework no matter when it was done. This is definitely something to look at when you are deciding where to apply, especially if your undergraduate work was done a while ago.
So the short answer is yes and no: the core list is consistent, but the details and time limits vary, which is why checking each program matters.
If you are still working on your degree and you know you want PA school (or something medical), you get to choose your major. Many majors already require most of the prerequisites you will need, and while it is efficient to pick one of those, you may have other interests worth pursuing too.
I majored in Biology, but in my graduating class there were all kinds of degrees, including Math and Accounting. Some other majors worth considering are Chemistry, Health Promotion, Biological Science, or Kinesiology, and your school may have other specific majors that get you what you need.
So it is not really what your major is that matters, it is what classes you take. Pick something you can succeed in and that lines up with the prerequisites, and you will be in good shape.
In our experience coaching applicants, the prerequisite list trips people up less than the planning around it. The applicants who struggle most are usually the ones who waited to map out their classes and then had to cram several science courses into one or two brutal semesters. If you space the hard sciences out and protect your grades, your application and your eventual transition into PA school both get easier.
The basic classes most programs require are typically these:
Biology with lab, usually 2 semesters
General chemistry with lab, usually 2 semesters
Anatomy and Physiology with lab, usually 2 semesters of a combined course, or one of each if they are separate
Statistics or Biostatistics. Some schools only accept one of these, so check the program's website and, if you are still unsure, call and ask specifically
Classes you might need and should consider taking if you can:
Psychology
Organic chemistry and/or biochemistry with lab (Organic Chemistry II was my only C+ in college and it was miserable, so unless you love chemistry, avoid it if it is optional. Mine was part of my Biology major, so I did not have a choice.)
Microbiology with lab
Other science electives
Always check each program you are interested in and crosscheck the list against what you have already taken or what your major requires.
Many programs require at least a C or B in each prerequisite regardless of your overall GPA, so a strong cumulative GPA will not cover for a weak grade in a required science.
Answer to question/header
Answer to question/header
Free Application Timeline -> https://www.thepaplatform.com/services/free-application-timeline/ [INSERT FREE LEAD MAGNET FORM OR HTML BLOCK HERE AND DELETE THIS TEXT BOX]
It is a good idea to check the website of any program you are interested in, where the prerequisites should be listed clearly, then crosscheck that against your completed courses or your major requirements. My Biology major only counted Anatomy as a general elective, so I took it over the summer since it was basically extra. I was worried about taking it at a different school than UGA, so I called the programs I was interested in to ask if that was okay, and the consensus was that as long as I had the prerequisites, it did not matter where I took them.
As daunting as the coursework seems, it really works in your favor once you start PA school. The pace is so fast that there is no time to review undergrad material, and programs need you ready and familiar with the science basics. Many medical schools do not even require anatomy, because they study it for a full year, while PA students often cover it in 1 semester!
These are tough classes, so if you can spread them out and earn better grades, that may help you. Some schools want at least a C or B in prerequisites no matter your overall GPA, so start planning early to get everything done and be ready to apply.
We walked through this same prerequisite list on episode 66 of The Pre-PA Club. Press play if you would rather hear it explained than read it, then come back for the checklist below.
Prereqs are where a lot of applications quietly fall apart, usually a year or two before anyone notices.
The common ones are General Biology 1, General Chemistry 1 and 2, Anatomy and Physiology 1 and 2, Statistics, Psychology, and Microbiology. But every program has its own list, its own expiration rules, and its own opinions about what counts. Check each one. Do not assume.
Aim for a B or better. A C technically satisfies the requirement at some programs, but it doesn't do anything for you, and with how competitive this is, "technically satisfied" isn't the goal.
And if you're not sure whether a specific course will be accepted, email the program and ask. They answer. It takes five minutes and can save you a whole semester.
What I cover
The prerequisite courses most programs want
Why grades of B or higher matter more than passing
Expiration dates on science coursework
Community college versus four-year credits
Emailing programs to confirm a course counts
Planning prereqs around your work schedule
Resources
Follow The Pre-PA Club: Apple Podcasts · Spotify · All episodes
Core prerequisites: 2 semesters each of biology, general chemistry, and anatomy and physiology, all with labs
Statistics or biostatistics is commonly required, but some schools accept only one
Recommended extras: psychology, microbiology, and sometimes organic chemistry or biochemistry
Your major matters less than the specific classes you complete
Some programs require prerequisites within the last 5-10 years [VERIFY]
Many programs want at least a C or B in each prerequisite regardless of overall GPA
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem dolore, alias, numquam enim ab voluptate id quam harum ducimus cupiditate similique quisquam et deserunt, recusandae.
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem dolore, alias, numquam enim ab voluptate id quam harum ducimus cupiditate similique quisquam et deserunt, recusandae.
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem dolore, alias, numquam enim ab voluptate id quam harum ducimus cupiditate similique quisquam et deserunt, recusandae.
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem dolore, alias, numquam enim ab voluptate id quam harum ducimus cupiditate similique quisquam et deserunt, recusandae.
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem dolore, alias, numquam enim ab voluptate id quam harum ducimus cupiditate similique quisquam et deserunt, recusandae.
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem dolore, alias, numquam enim ab voluptate id quam harum ducimus cupiditate similique quisquam et deserunt, recusandae.
Pre-PA Counseling -> https://www.thepaplatform.com/services/pre-pa-counseling/ [INSERT HTML SERVICE BLOCK CTA HERE AND DELETE THIS TEXT BOX]
PA school prerequisites look intimidating, but they are very doable when you plan ahead and pace the hard sciences. Check each program's exact list early, protect your grades, and you will set yourself up for a smoother application and a stronger start in school. If you want help mapping out your coursework and timeline, our free resources and coaching are here whenever you need them.
How to Prepare for PA School in Undergrad
CASPA GPA Calculator
PA School Application Timeline
How to Choose Where to Apply

The Pre-PA Newsletter
Real PA admissions updates, new free resources, this week's podcast, and the one thing to focus on this week of the cycle.
Your email address is safe with us .We never share your information with anyone