Mission Trips as a PA: Inside Hands of Esperanza

Mission Trips as a PA: Inside Hands of Esperanza

By: Savanna Perry, PA-C

TL;DR

Hands of Esperanza is a PA-run nonprofit founded out of a Nova Southeastern PA school mission trip, providing healthcare to rural Guatemala. In this Pre-PA Club Podcast conversation, founders Ashley and Eryn share how their trips work, what PAs can do abroad, the community impact, and practical ways pre-PAs, students, and PAs can get involved.

Last Updated: June 12, 2026
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How did Hands of Esperanza get started?

I'm chatting with Ashley and Eryn from Hands of Esperanza, a nonprofit providing healthcare to rural areas of Guatemala that grew out of a PA school mission trip. Ashley is a transplant and hepatobiliary surgical oncology PA in Atlanta, and Eryn is an emergency room PA in Tampa. They both went to Nova Southeastern University in Orlando.

The group started Ashley's first year of PA school in 2014, because Nova didn't have a mission trip and a group of students passionate about global health wanted to create a legacy. A trusted professor connected them with an organization she trusted in Guatemala. They took their first trip in 2015 after their didactic year, with about 20 students, one PA, and one nurse. They did three days of remote rural clinics plus hospital and orphanage volunteering. They were hooked, and in June 2019 they formed their own nonprofit to fundraise for their biggest project: a multi-specialty medical and surgical center to provide sustainable, year-round care.

In this post:

What actually happens on a PA mission trip?

Their model is unique because it gives PA students their first clinical experience between the didactic and clinical years, putting their diagnostic skills to the test. The first day they hike to a remote village, unpack, set up rooms, and triage patients into primary care, pediatric, and OB/GYN stations. They typically see 200 to 300 patients a day in bursts, since people walk three to four hours from different villages. Over four days at a rudimentary school with open air walls and dirt or concrete floors, students learn to work without labs or x-rays, relying on history taking and physical exam skills.

After the four clinic days, they spend a full day volunteering in a hospital, participating in ER triage, labor and delivery, surgeries, and rounds. They also build stoves with chimneys to reduce the respiratory illness caused by cooking over open flames, having built 25 stoves in one year, and they install water filtration systems that last about 20 years. Patient education is central, including teaching families to boil water and treat conditions like scabies. Many patients speak a Mayan dialect called Poqomchi', so they translate from English to Spanish to Poqomchi'.

In Our Experience

This conversation genuinely inspired me to think about what we as PAs can do to serve patients and people more. I've been on mission trips to Kenya and El Salvador myself, and my biggest tip matches theirs: stay flexible. On my derm-focused Kenya trip, I was the only one who packed a stethoscope, and it quickly became a multi-specialty clinic, so expect the unexpected.

What can a PA do on a mission trip, and what do they treat?

A common question is whether a PA still needs a supervising or collaborating physician abroad. The main barrier is ordering medications in the U.S. to bring along, which requires a physician prescriber to sign off. Once in Guatemala, they are not required to have a physician accompany them. All of their medical licenses are registered with the Guatemalan Ministry of Health, and they are transparent with patients that students are being supervised. For surgical trips, a surgeon and anesthesiologist or CRNA would likely be required, but for basic primary care they don't have laws requiring a physician present. With 15 PAs spanning ICU, pediatrics, ER, and surgery, the team has broad expertise.

Medically, they see a lot of upper respiratory issues, GI issues from waterborne worms, and aches and pains from manual labor. They bring nebulizers, deworming medication, and reading glasses, and they perform procedures like draining abscesses, removing superficial lipomas, removing foreign bodies, and even removing a Nexplanon. A major focus is OB/GYN and public health, and the rate of STDs has dropped dramatically over five years thanks to treatment and education. The biggest barrier is nutrition, since about 83% of the local population lives below Guatemala's poverty line. [VERIFY]


Every Pre-PA Should Know...

On a remote mission trip you often work without labs or imaging, so your history taking and physical exam skills become your most important tools.


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How can pre-PAs, students, and PAs get involved?

There are many ways to help. The first is simply spreading awareness of the mission. The second is donating, whether financially, with supplies (their website lists commonly used over the counter medications), or with your time as a volunteer. The third is volunteering through their partner organization in Guatemala, Living to Serve, which runs trips year round for all ages and abilities, including options that don't require hiking. Pre-PAs interested in public health education can find a role there too.

On costs, building a stove runs about $200 to $250, and the conservative estimate for the two-level multi-specialty clinic with a surgery center is $450,000, with land already purchased and a perimeter wall under construction. [VERIFY] Their mission trip costs about $1,100 including flight and main meals, which is lower than many comparable trips, and many students fund it through GoFundMe. [VERIFY] Their top advice for first-time mission trip participants is to stay flexible and go in open minded without rigid expectations, which, as they note, is exactly what being a PA requires.

Need to Know:

  • Hands of Esperanza is a PA-run nonprofit serving rural Guatemala

  • Trips give PA students early clinical experience using exam skills alone

  • PAs generally don't need a physician present for basic primary care abroad

  • Always register licenses and be transparent that students are supervised

  • You can help by spreading awareness, donating, or volunteering time

  • Flexibility and an open mind are essential on any mission trip


Listen to the full episode

We talked through this on The Pre-PA Club podcast. Press play for the full episode.

Episode show notes & key takeaways

I found Hands of Esperanza recently and immediately wanted to tell you about it.

It's a PA-run medical mission organization working in Guatemala, and what I love is that it isn't just clinics and go home. They're doing community development work too - building stoves so families aren't breathing smoke indoors, and putting together a multi-specialty medical center that stays after the volunteers leave.

Ashley and Erin came on to talk about how the nonprofit started and what led them there. If you've been looking for a way to use your training that goes beyond a job, or you're a student wondering how PAs end up doing global health work, this is a good place to start listening.

What we talk about

  • How Hands of Esperanza got started

  • Medical mission work in Guatemala

  • Building stoves and why respiratory health improved

  • Creating a lasting multi-specialty center

  • How PAs and students can get involved

  • Doing this work responsibly instead of as a photo op

Resources

Episode: Mission Trips as a Physician Assistant - with Hands of Esperanza, a PA-run Non-Profit · Follow The Pre-PA Club on Apple Podcasts or Spotify · Browse all episodes

FAQ

Can a PA go on a medical mission trip?

Yes. PAs regularly go on medical mission trips. For basic primary care abroad, a physician often isn't legally required to be present, though ordering medications in the U.S. needs a physician prescriber's sign-off.

What is Hands of Esperanza?

Hands of Esperanza is a PA-run nonprofit, founded out of a Nova Southeastern PA school mission trip, that provides healthcare and public health projects to rural areas of Guatemala.

What do PAs treat on mission trips?

Common cases include upper respiratory illness, GI issues from waterborne worms, and aches from manual labor. They also perform minor procedures and focus heavily on patient education and OB/GYN care.

How much does a PA mission trip cost?

The Hands of Esperanza trip costs about $1,100 including flight and main meals, which is lower than many comparable trips. Many students fundraise through platforms like GoFundMe. [VERIFY]

How can pre-PA students get involved in mission work?

You can spread awareness, donate funds or supplies, or volunteer your time, including through partner organization Living to Serve, which runs year-round trips for all ages and ability levels.

What is the best advice for a first mission trip?

Stay flexible and go in with an open mind and no rigid expectations. Roles shift constantly on the ground, which, fittingly, is also what being a PA is all about.

CLOSING

Medical missions are a powerful way to serve and to grow as a future provider, and Hands of Esperanza shows what a PA-led effort can build. If global health is calling you, start by spreading the word, donating, or exploring a trip with their partner Living to Serve. And if you want to weave service into your pre-PA journey, we're happy to help you think it through.

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You May Also Like:

  • Global Health Opportunities for Pre-PAs

  • Finding Volunteer Hours for PA School

  • Day in the Life PA Specialty Series

  • Building a Standout PA Application Through Service

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